Parenteral adjuvant effects of an enterotoxigenic Escherichia coli (ETEC) natural heat-labile toxin variant

Parenteral adjuvant effects of an enterotoxigenic Escherichia coli (ETEC) natural heat-labile toxin variant

Native type I heat-labile toxins (LTs) produced by enterotoxigenic Escherichia coli (ETEC) strains exert strong adjuvant effects on both antibody and T cell responses to soluble and particulate antigens following co-administration via mucosal routes. However, inherent enterotoxicity and neurotoxicit...

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Bibliographic Details
Main Authors: Catarina Joelma Magalhães Braga, Juliana Falcão Rodrigues, Yordanka eMedina-Armenteros, Luis Ernesto Farinha-Arcieri, Armando Morais Ventura, Silvia Beatriz Boscardin, Maria Elisabete Sbrogio-Almeida, Luis Carlos de Souza Ferreira
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Immunology
Subjects:
HIV-1
Vaccines
adjuvants
heat-labile toxin
p24
intra-dermal immunisation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00487/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00487/full

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