Depletion of acetate-producing bacteria from the gut microbiota facilitates cognitive impairment through the gut-brain neural mechanism in diabetic mice

Depletion of acetate-producing bacteria from the gut microbiota facilitates cognitive impairment through the gut-brain neural mechanism in diabetic mice

Abstract Background Modification of the gut microbiota has been reported to reduce the incidence of type 1 diabetes mellitus (T1D). We hypothesized that the gut microbiota shifts might also have an effect on cognitive functions in T1D. Herein we used a non-absorbable antibiotic vancomycin to modify...

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Bibliographic Details
Main Authors: Hong Zheng, Pengtao Xu, Qiaoying Jiang, Qingqing Xu, Yafei Zheng, Junjie Yan, Hui Ji, Jie Ning, Xi Zhang, Chen Li, Limin Zhang, Yuping Li, Xiaokui Li, Weihong Song, Hongchang Gao
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Microbiome
Subjects:
Acetate
Metabolome
Diabetes
Cognition
Microbiome
Gut-brain axis
Online Access:https://doi.org/10.1186/s40168-021-01088-9

Internet

https://doi.org/10.1186/s40168-021-01088-9

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