The therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3′,5′-monophosphate (Epac) for central nervous system trauma

The therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3′,5′-monophosphate (Epac) for central nervous system trauma

Millions of people worldwide are affected by traumatic spinal cord injury, which usually results in permanent sensorimotor disability. Damage to the spinal cord leads to a series of detrimental events including ischaemia, haemorrhage and neuroinflammation, which over time result in further neural ti...

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Bibliographic Details
Main Authors: Alba Guijarro-Belmar, Dominik Mateusz Domanski, Xuenong Bo, Derryck Shewan, Wenlong Huang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
astrocytes; axonal regeneration; camp; central nervous system regeneration; epac; glial scar; microglia; neuroinflammation; neurons; spinal cord; spinal cord injury; traumatic spinal cord injury
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=3;spage=460;epage=469;aulast=Guijarro-Belmar

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=3;spage=460;epage=469;aulast=Guijarro-Belmar

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