Alisol A Alleviates Arterial Plaque by Activating AMPK/SIRT1 Signaling Pathway in apoE-Deficient Mice

Alisol A Alleviates Arterial Plaque by Activating AMPK/SIRT1 Signaling Pathway in apoE-Deficient Mice

Alismatis Rhizoma (zexie), an herb used in traditional Chinese medicine, exhibits hypolipemic, anti-inflammation and anti-atherosclerotic activities. Alisol A is one of the main active ingredients in Alismatis Rhizoma extract. In this study, we investigate the role of alisol A in anti-atherosclerosi...

Full description

Bibliographic Details
Main Authors: Ke Wang, Beibei Zhang, Dingzhong Song, Jianqiang Xi, Wusi Hao, Jie Yuan, Chenyu Gao, Zhongbao Cui, Zhihong Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
Alisol A
AMPK/SIRT1 pathway
anti-atherogenesis
anti-inflammation
PPARα/δ
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.580073/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.580073/full

Similar Items