CCL20/TNF/VEGFA Cytokine Secretory Phenotype of Tumor-Associated Macrophages Is a Negative Prognostic Factor in Cutaneous Melanoma

CCL20/TNF/VEGFA Cytokine Secretory Phenotype of Tumor-Associated Macrophages Is a Negative Prognostic Factor in Cutaneous Melanoma

TAMs constitute a large fraction of infiltrating immune cells in melanoma tissues, but their significance for clinical outcomes remains unclear. We explored diverse TAM parameters in clinically relevant primary cutaneous melanoma samples, including density, location, size, and polarization marker ex...

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Bibliographic Details
Main Authors: Alba Gutiérrez-Seijo, Elena García-Martínez, Celia Barrio-Alonso, Miriam Pareja-Malagón, Alejandra Acosta-Ocampo, María Eugenia Fernández-Santos, Amaya Puig-Kröger, Verónica Parra-Blanco, Enrique Mercader, Iván Márquez-Rodas, José Antonio Avilés-Izquierdo, Rafael Samaniego, Paloma Sánchez-Mateos
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
CCL20
TNF
VEGFA
melanoma
metastasis
TAM
Online Access:https://www.mdpi.com/2072-6694/13/16/3943

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https://www.mdpi.com/2072-6694/13/16/3943

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