Impaired release of antimicrobial peptides into nasal fluid of hyper-IgE and CVID patients.

BACKGROUND: Patients with primary immunodeficiency (PID) often suffer from frequent respiratory tract infections. Despite standard treatment with IgG-substitution and antibiotics many patients do not improve significantly. Therefore, we hypothesized that additional immune deficits may be present amo...

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Bibliographic Details
Main Authors: Andreas Cederlund, Marie Olliver, Rokeya Sultana Rekha, Monica Lindh, Lennart Lindbom, Staffan Normark, Birgitta Henriques-Normark, Jan Andersson, Birgitta Agerberth, Peter Bergman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3246483?pdf=render