Finding associations in a heterogeneous setting: statistical test for aberration enrichment
Abstract Most two-group statistical tests find broad patterns such as overall shifts in mean, median, or variance. These tests may not have enough power to detect effects in a small subset of samples, e.g., a drug that works well only on a few patients. We developed a novel statistical test targetin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-04-01
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| Series: | Genome Medicine |
| Online Access: | https://doi.org/10.1186/s13073-021-00864-4 |