Evidence for X-chromosomal schizophrenia associated with microRNA alterations.

Schizophrenia is a severe disabling brain disease affecting about 1% of the population. Individual microRNAs (miRNAs) affect moderate downregulation of gene expression. In addition, components required for miRNA processing and/or function have also been implicated in X-linked mental retardation, neu...

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Bibliographic Details
Main Authors: Jinong Feng, Guihua Sun, Jin Yan, Katie Noltner, Wenyan Li, Carolyn H Buzin, Jeff Longmate, Leonard L Heston, John Rossi, Steve S Sommer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2699475?pdf=render