HeLa-CCL2 cell heterogeneity studied by single-cell DNA and RNA sequencing.

The HeLa cells are the earliest and mostly used laboratory human cells for biomedical particularly cancer research. They were derived from a patient's cervical cancerous tissue, and are known for their heterogeneous cellular origin and variable genomic landscapes. Single-cell sequencing techniq...

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Bibliographic Details
Main Authors: Wan-Er Hu, Xin Zhang, Qiu-Fang Guo, Jing-Wei Yang, Yuan Yang, Shi-Cheng Wei, Xiao-Dong Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225466