Comparison of normalization approaches for gene expression studies completed with high-throughput sequencing.
Normalization of RNA-Seq data has proven essential to ensure accurate inferences and replication of findings. Hence, various normalization methods have been proposed for various technical artifacts that can be present in high-throughput sequencing transcriptomic studies. In this study, we set out to...
Main Authors: | Farnoosh Abbas-Aghababazadeh, Qian Li, Brooke L Fridley |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC6209231?pdf=render |
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