Comparison of normalization approaches for gene expression studies completed with high-throughput sequencing.

Normalization of RNA-Seq data has proven essential to ensure accurate inferences and replication of findings. Hence, various normalization methods have been proposed for various technical artifacts that can be present in high-throughput sequencing transcriptomic studies. In this study, we set out to...

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Bibliographic Details
Main Authors: Farnoosh Abbas-Aghababazadeh, Qian Li, Brooke L Fridley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6209231?pdf=render