Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development.

In insects, precisely timed periodic pulses of the molting hormone ecdysone control major developmental transitions such as molts and metamorphosis. The synthesis and release of ecdysone, a steroid hormone, is itself controlled by PTTH (prothoracicotopic hormone). PTTH transcript levels oscillate wi...

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Bibliographic Details
Main Authors: Qiuxiang Ou, Adam Magico, Kirst King-Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3181225?pdf=render