Preclinical studies of N3-O-toluyl-fluorouracil-loaded lipid-based nanosuspensions in H22-bearing mice

Juan Zhang, Min Li, Zhihong Liu, Lili Wang, Yongjun Liu, Na Zhang School of Pharmaceutical Science, Shandong University, Ji’nan, People’s Republic of China Purpose: N3-O-toluyl-fluorouracil (TFU) is a potential antitumor prodrug of 5-fluorouracil (5-FU), but its poor solubilit...

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Bibliographic Details
Main Authors: Zhang J, Li M, Liu Z, Wang L, Liu Y, Zhang N
Format: Article
Language:English
Published: Dove Medical Press 2014-05-01
Series:International Journal of Nanomedicine
Online Access:http://www.dovepress.com/preclinical-studies-of-n3-o-toluyl-fluorouracil-loaded-lipid-based-nan-a17052