Digital PCR validates 8q dosage as prognostic tool in uveal melanoma.

Digital PCR validates 8q dosage as prognostic tool in uveal melanoma.

Uveal melanoma (UM) development and progression is correlated with specific molecular changes. Recurrent mutations in GNAQ and GNA11 initiate UM development while tumour progression is correlated with monosomy of chromosome 3 and gain of chromosome 8q. Hence, molecular analysis of UM is useful for d...

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Bibliographic Details
Main Authors: Mieke Versluis, Mark J de Lange, Sake I van Pelt, Claudia A L Ruivenkamp, Wilma G M Kroes, Jinfeng Cao, Martine J Jager, Gre P M Luyten, Pieter A van der Velden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4357379?pdf=render

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http://europepmc.org/articles/PMC4357379?pdf=render

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