Burst-time-dependent plasticity robustly guides ON/OFF segregation in the lateral geniculate nucleus.

Spontaneous retinal activity (known as "waves") remodels synaptic connectivity to the lateral geniculate nucleus (LGN) during development. Analysis of retinal waves recorded with multielectrode arrays in mouse suggested that a cue for the segregation of functionally distinct (ON and OFF) r...

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Bibliographic Details
Main Authors: Julijana Gjorgjieva, Taro Toyoizumi, Stephen J Eglen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2790088?pdf=render