Identification of Key Candidate Proteins and Pathways Associated with Temozolomide Resistance in Glioblastoma Based on Subcellular Proteomics and Bioinformatical Analysis

Identification of Key Candidate Proteins and Pathways Associated with Temozolomide Resistance in Glioblastoma Based on Subcellular Proteomics and Bioinformatical Analysis

TMZ resistance remains one of the main reasons why treatment of glioblastoma (GBM) fails. In order to investigate the underlying proteins and pathways associated with TMZ resistance, we conducted a cytoplasmic proteome research of U87 cells treated with TMZ for 1 week, followed by differentially exp...

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Bibliographic Details
Main Authors: Guo-zhong Yi, Wei Xiang, Wen-yan Feng, Zi-yang Chen, Yao-min Li, Sheng-ze Deng, Man-lan Guo, Liang Zhao, Xue-gang Sun, Min-yi He, Song-tao Qi, Ya-wei Liu
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/5238760

Internet

http://dx.doi.org/10.1155/2018/5238760

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