The human <it>PINK1 </it>locus is regulated <it>in vivo </it>by a non-coding natural antisense RNA during modulation of mitochondrial function
<p>Abstract</p> <p>Background</p> <p>Mutations in the PTEN induced putative kinase 1 (<it>PINK1</it>) are implicated in early-onset Parkinson's disease. PINK1 is expressed abundantly in mitochondria rich tissues, such as skeletal muscle, where it plays...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2007-03-01
|
Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/8/74 |