The human <it>PINK1 </it>locus is regulated <it>in vivo </it>by a non-coding natural antisense RNA during modulation of mitochondrial function

<p>Abstract</p> <p>Background</p> <p>Mutations in the PTEN induced putative kinase 1 (<it>PINK1</it>) are implicated in early-onset Parkinson's disease. PINK1 is expressed abundantly in mitochondria rich tissues, such as skeletal muscle, where it plays...

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Bibliographic Details
Main Authors: Wahlestedt Claes, Rooyackers Olav, Fredriksson Katarina, Lassmann Timo, Faghihi Mohammad A, Petrovic Natasa, Scheele Camilla, Good Liam, Timmons James A
Format: Article
Language:English
Published: BMC 2007-03-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/8/74