A pilot of the feasibility and usefulness of an aged obese model for use in stroke research [version 1; peer review: 2 approved]

Background: Animal models of stroke have been criticised as having poor predictive validity, lacking risk factors prevalent in an aging population. This pilot study examined the development of comorbidities in a combined aged and high-fat diet model, and then examined the feasibility of modelling st...

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Bibliographic Details
Main Authors: Annastazia E. Learoyd, Ryan Calmus, Chelsea N. Cunningham, Tim J. England, Tracy D. Farr, Kevin C.F. Fone, David A. Kendall, Saoirse E. O’Sullivan, Rebecca C. Trueman
Format: Article
Language:English
Published: Wellcome 2021-05-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/6-104/v1