Has the rate of CD4 cell count decline before initiation of antiretroviral therapy changed over the course of the Dutch HIV epidemic among MSM?

Has the rate of CD4 cell count decline before initiation of antiretroviral therapy changed over the course of the Dutch HIV epidemic among MSM?

Studies suggest that the HIV-1 epidemic in the Netherlands may have become more virulent, leading to faster disease progression if untreated. Analysis of CD4 cell count decline before antiretroviral therapy (ART) initiation, a surrogate marker for disease progression, may be hampered by informative...

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Bibliographic Details
Main Authors: Luuk Gras, Ronald B Geskus, Suzanne Jurriaans, Margreet Bakker, Ard van Sighem, Daniela Bezemer, Christophe Fraser, Jan M Prins, Ben Berkhout, Frank de Wolf, ATHENA National Observational Cohort
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3664616?pdf=render

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