Has the rate of CD4 cell count decline before initiation of antiretroviral therapy changed over the course of the Dutch HIV epidemic among MSM?

Studies suggest that the HIV-1 epidemic in the Netherlands may have become more virulent, leading to faster disease progression if untreated. Analysis of CD4 cell count decline before antiretroviral therapy (ART) initiation, a surrogate marker for disease progression, may be hampered by informative...

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Bibliographic Details
Main Authors: Luuk Gras, Ronald B Geskus, Suzanne Jurriaans, Margreet Bakker, Ard van Sighem, Daniela Bezemer, Christophe Fraser, Jan M Prins, Ben Berkhout, Frank de Wolf, ATHENA National Observational Cohort
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3664616?pdf=render