Ground state robustness as an evolutionary design principle in signaling networks.

The ability of an organism to survive depends on its capability to adapt to external conditions. In addition to metabolic versatility and efficient replication, reliable signal transduction is essential. As signaling systems are under permanent evolutionary pressure one may assume that their structu...

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Bibliographic Details
Main Authors: Onder Kartal, Oliver Ebenhöh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2779451?pdf=render