Hymyc1 downregulation promotes stem cell proliferation in Hydra vulgaris.

Hydra is a unique model for studying the mechanisms underlying stem cell biology. The activity of the three stem cell lineages structuring its body constantly replenishes mature cells lost due to normal tissue turnover. By a poorly understood mechanism, stem cells are maintained through self-renewal...

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Bibliographic Details
Main Authors: Alfredo Ambrosone, Valentina Marchesano, Angela Tino, Bert Hobmayer, Claudia Tortiglione
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22292012/pdf/?tool=EBI