Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases

Prc, also known previously as Tsp, is the founding member of the carboxyl-terminal processing protease (CTP) family of PDZ domain-containing proteases that include CtpA and CtpB. The substrate-binding PDZ domain is responsible for regulating the protease activity of CTP proteases; however, the regul...

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Bibliographic Details
Main Authors: Chuang-Kai Chueh, Nilanjan Som, Lu-Chu Ke, Meng-Ru Ho, Manjula Reddy, Chung-I Chang
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mBio
Subjects:
ctp
prc
Online Access:https://doi.org/10.1128/mBio.01129-19