Transcriptional regulation of VEGFA by the endoplasmic reticulum stress transducer OASIS in ARPE-19 cells.

BACKGROUND: Vascular endothelial growth factor-A (VEGFA) is the main mediator of angiogenesis. Angiogenesis plays important roles not only in many physiological processes, but also in the pathophysiology of many diseases. VEGFA is one of the therapeutic targets of treatment for ocular diseases with...

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Main Authors: Hidetaka Miyagi, Soshi Kanemoto, Atsushi Saito, Rie Asada, Hideo Iwamoto, Soutarou Izumi, Miori Kido, Fumi Gomi, Kohji Nishida, Yoshiaki Kiuchi, Kazunori Imaizumi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3559390?pdf=render