Phenotype enhancement screen of a regulatory spx mutant unveils a role for the ytpQ gene in the control of iron homeostasis.

Spx is a global regulator of genes that are induced by disulfide stress in Bacillus subtilis. The regulon that it governs is comprised of over 120 genes based on microarray analysis, although it is not known how many of these are under direct Spx control. Most of the Spx-regulated genes (SRGs) are o...

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Bibliographic Details
Main Authors: Peter Zuber, Shefali Chauhan, Praseeda Pilaka, Michiko M Nakano, Sairam Gurumoorthy, Ann A Lin, Skye M Barendt, Bui Khanh Chi, Haike Antelmann, Ulrike Mäder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3176815?pdf=render