Site-switchable mono-O-allylation of polyols

Site-switchable mono-O-allylation of polyols

Selective manipulation of one functional group, out of many repeatedly occurring in a substrate, represents a grand challenge in chemistry. Here, the authors report a Pd/Lewis acid cocatalytic system that achieves not only site-selective, but also site-switchable mono-O-allylation of polyols.

Bibliographic Details
Main Authors: Hua Tang, Yu-Biao Tian, Hongyan Cui, Ren-Zhe Li, Xia Zhang, Dawen Niu
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19348-x
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spelling doaj-6cf8f138943144b498ec6401106dd12b2021-05-11T08:34:05ZengNature Publishing GroupNature Communications2041-17232020-11-0111111010.1038/s41467-020-19348-xSite-switchable mono-O-allylation of polyolsHua Tang0Yu-Biao Tian1Hongyan Cui2Ren-Zhe Li3Xia Zhang4Dawen Niu5Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan UniversityDepartment of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan UniversityDepartment of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan UniversityDepartment of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan UniversityDepartment of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan UniversityDepartment of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan UniversitySelective manipulation of one functional group, out of many repeatedly occurring in a substrate, represents a grand challenge in chemistry. Here, the authors report a Pd/Lewis acid cocatalytic system that achieves not only site-selective, but also site-switchable mono-O-allylation of polyols.https://doi.org/10.1038/s41467-020-19348-x
collection DOAJ
language English
format Article
sources DOAJ
author Hua Tang
Yu-Biao Tian
Hongyan Cui
Ren-Zhe Li
Xia Zhang
Dawen Niu
spellingShingle Hua Tang
Yu-Biao Tian
Hongyan Cui
Ren-Zhe Li
Xia Zhang
Dawen Niu
Site-switchable mono-O-allylation of polyols
Nature Communications
author_facet Hua Tang
Yu-Biao Tian
Hongyan Cui
Ren-Zhe Li
Xia Zhang
Dawen Niu
author_sort Hua Tang
title Site-switchable mono-O-allylation of polyols
title_short Site-switchable mono-O-allylation of polyols
title_full Site-switchable mono-O-allylation of polyols
title_fullStr Site-switchable mono-O-allylation of polyols
title_full_unstemmed Site-switchable mono-O-allylation of polyols
title_sort site-switchable mono-o-allylation of polyols
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-11-01
description Selective manipulation of one functional group, out of many repeatedly occurring in a substrate, represents a grand challenge in chemistry. Here, the authors report a Pd/Lewis acid cocatalytic system that achieves not only site-selective, but also site-switchable mono-O-allylation of polyols.
url https://doi.org/10.1038/s41467-020-19348-x
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AT yubiaotian siteswitchablemonooallylationofpolyols
AT hongyancui siteswitchablemonooallylationofpolyols
AT renzheli siteswitchablemonooallylationofpolyols
AT xiazhang siteswitchablemonooallylationofpolyols
AT dawenniu siteswitchablemonooallylationofpolyols
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