Site-switchable mono-O-allylation of polyols
Selective manipulation of one functional group, out of many repeatedly occurring in a substrate, represents a grand challenge in chemistry. Here, the authors report a Pd/Lewis acid cocatalytic system that achieves not only site-selective, but also site-switchable mono-O-allylation of polyols.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2020-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-19348-x |
| Summary: | Selective manipulation of one functional group, out of many repeatedly occurring in a substrate, represents a grand challenge in chemistry. Here, the authors report a Pd/Lewis acid cocatalytic system that achieves not only site-selective, but also site-switchable mono-O-allylation of polyols. |
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| ISSN: | 2041-1723 |