K13 blocks KSHV lytic replication and deregulates vIL6 and hIL6 expression: a model of lytic replication induced clonal selection in viral oncogenesis.

K13 blocks KSHV lytic replication and deregulates vIL6 and hIL6 expression: a model of lytic replication induced clonal selection in viral oncogenesis.

Accumulating evidence suggests that dysregulated expression of lytic genes plays an important role in KSHV (Kaposi's sarcoma associated herpesvirus) tumorigenesis. However, the molecular events leading to the dysregulation of KSHV lytic gene expression program are incompletely understood.We hav...

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Bibliographic Details
Main Authors: Jinshun Zhao, Vasu Punj, Hittu Matta, Lucia Mazzacurati, Sandra Schamus, Yanqiang Yang, Tianbing Yang, Yan Hong, Preethello M Chaudhary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2020437?pdf=render

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http://europepmc.org/articles/PMC2020437?pdf=render

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