Hypermethylation of the microRNA miR-124, miR-125b, miR-127, and miR-129 in ovarian carcinoma is involved in suppression of their expression and associated with both the development and progression of ovarian cancer

Hypermethylation of the microRNA miR-124, miR-125b, miR-127, and miR-129 in ovarian carcinoma is involved in suppression of their expression and associated with both the development and progression of ovarian cancer

Rationale: We have previously identified a group of microRNA genes (MIR-107, MIR-1258, MIR-130b, MIR-34b/c, MIR-9-1, MIR-9-3 et al.), whose methylation was involved into the development and progression of ovarian cancer. Aim: To expand the range of microRNA genes hypermethylated in ovarian cancer an...

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Bibliographic Details
Main Authors: E. A. Braga, I. V. Pronina, D. O. Utkin, E. A. Filippova, A. M. Burdennyy, V. I. Loginov, M. V. Fridman, T. P. Kazubskaya, N. E. Kushlinskii
Format: Article
Language:Russian
Published: MONIKI 2019-02-01
Series:Alʹmanah Kliničeskoj Mediciny
Subjects:
ovarian cancer
microrna genes
hypermethylation
metastasis
peritoneal macro-metastases
Online Access:https://www.almclinmed.ru/jour/article/view/962

Internet

https://www.almclinmed.ru/jour/article/view/962

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