Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides
Fibrosis results from the excessive accumulation of extracellular matrix in chronically injured tissue. The fibrotic process is governed by crosstalk between many signaling pathways. The search for an effective treatment is further complicated by the fact that there is a degree of tissue-specificity...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-06-01
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| Series: | Biomedicines |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2227-9059/6/3/74 |