SHBG is an important factor in stemness induction of cells by DHT in vitro and associated with poor clinical features of prostate carcinomas.

Androgen plays a vital role in prostate cancer development. However, it is not clear whether androgens influence stem-like properties of prostate cancer, a feature important for prostate cancer progression. In this study, we show that upon DHT treatment in vitro, prostate cancer cell lines LNCaP and...

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Bibliographic Details
Main Authors: Yuanyuan Ma, Dongming Liang, Jian Liu, Jian-Guo Wen, Einar Servoll, Gudmund Waaler, Thorstein Sæter, Karol Axcrona, Ljiljana Vlatkovic, Ulrika Axcrona, Elisabeth Paus, Yue Yang, Zhiqian Zhang, Gunnar Kvalheim, Jahn M Nesland, Zhenhe Suo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3728318?pdf=render