Exosomal microRNA-144 from bone marrow-derived mesenchymal stem cells inhibits the progression of non-small cell lung cancer by targeting CCNE1 and CCNE2

Exosomal microRNA-144 from bone marrow-derived mesenchymal stem cells inhibits the progression of non-small cell lung cancer by targeting CCNE1 and CCNE2

Abstract Background Mesenchymal stem cells (MSCs) are pluripotent mesenchymal cells present in various adult tissues. MSCs secrete exosomes as regulators of the tumor niche, with involvement in tumorigenesis and metastasis. The regulatory role of microRNAs (miRs or miRNAs) in MSCs via targeting cycl...

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Bibliographic Details
Main Authors: Yuan Liang, Dalin Zhang, Linlin Li, Tian Xin, Yuwei Zhao, Rui Ma, Jiang Du
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Stem Cell Research & Therapy
Subjects:
Non-small cell lung cancer
Bone marrow-derived mesenchymal stem cells
Exosomes
MicroRNA-144
Cyclin E1
Cyclin E2
Online Access:http://link.springer.com/article/10.1186/s13287-020-1580-7

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http://link.springer.com/article/10.1186/s13287-020-1580-7

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