Biphasic Effect of Curcumin on Morphine Tolerance: A Preliminary Evidence from Cytokine/Chemokine Protein Array Analysis

The aim of this study was to evaluate the effect of curcumin on morphine tolerance and the corresponding cytokine/chemokine changes. Male ICR mice were made tolerant to morphine by daily subcutaneous injection for 7 days. Intraperitoneal injections of vehicle, low-dose or high-dose curcumin were adm...

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Bibliographic Details
Main Authors: Jui-An Lin, Jenn-Han Chen, Yuan-Wen Lee, Chao-Shun Lin, Ming-Hui Hsieh, Chuen-Chau Chang, Chih-Shung Wong, Judy Ju-Yi Chen, Geng-Chang Yeh, Feng-Yen Lin, Ta-Liang Chen
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1093/ecam/neq018