Purification of Modified Therapeutic Proteins Available on the Market: An Analysis of Chromatography-Based Strategies

Proteins, which have inherent biorecognition properties, have long been used as therapeutic agents for the treatment of a wide variety of clinical indications. Protein modification through covalent attachment to different moieties improves the therapeutic’s pharmacokinetic properties, affinity, stab...

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Bibliographic Details
Main Authors: Calef Sánchez-Trasviña, Miguel Flores-Gatica, Daniela Enriquez-Ochoa, Marco Rito-Palomares, Karla Mayolo-Deloisa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.717326/full