Generation, localization and functions of macrophages during the development of testis

The developmental origins and functions of testis macrophages remain incompletely characterized. Here, the authors show, using histology, high-dimensional mass cytometry and cell fate-mapping data, that interstitial and peritubular macrophages originate from distinct precursors and contribute distin...

Full description

Bibliographic Details
Main Authors: Emmi Lokka, Laura Lintukorpi, Sheyla Cisneros-Montalvo, Juho-Antti Mäkelä, Sofia Tyystjärvi, Venla Ojasalo, Heidi Gerke, Jorma Toppari, Pia Rantakari, Marko Salmi
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18206-0