Differential Notch and TGFβ Signaling in Primary Colorectal Tumors and Their Corresponding Metastases
Background: Loss of epithelial morphology and the acquisition of mesenchymal characteristics may contribute to metastasis formation during colorectal tumorigenesis. The Wnt, Notch and TGFβ signaling pathways control tissue homeostasis and tumor development in the gut. The relationship between the ac...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2008-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.1155/2008/839076 |