Accelerated Evolution of Limb-Related Gene Hoxd11 in the Common Ancestor of Cetaceans and Ruminants (Cetruminantia)

Accelerated Evolution of Limb-Related Gene Hoxd11 in the Common Ancestor of Cetaceans and Ruminants (Cetruminantia)

Reduced numbers of carpal and tarsal bones (wrist and ankle joints) are extensively observed in the clade of Cetacea and Ruminantia (Cetruminantia). Homebox D11 (Hoxd11) is one of the important genes required for limb development in mammals. Mutations in Hoxd11 can lead to defects in particular bone...

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Bibliographic Details
Main Authors: Jun Li, Songyang Shang, Na Fang, Yubo Zhu, Junpeng Zhang, David M. Irwin, Shuyi Zhang, Zhe Wang
Format: Article
Language:English
Published: Oxford University Press 2020-02-01
Series:G3: Genes, Genomes, Genetics
Subjects:
limb
carpal
tarsal
5′hox genes
hoxd11
mutation
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400512

Internet

http://g3journal.org/lookup/doi/10.1534/g3.119.400512

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