Secondhand Smoke Decreased Excitability and Altered Action Potential Characteristics of Cardiac Vagal Neurons in Mice

Secondhand Smoke Decreased Excitability and Altered Action Potential Characteristics of Cardiac Vagal Neurons in Mice

Background: Secondhand smoke (SHS), a major indoor pollutant, is a significant risk factor for cardiovascular morbidity and mortality including arrhythmias and sudden cardiac death. Exposure to SHS can produce autonomic imbalance, as evidenced by reduced heart rate variability (HRV)—a clinical metri...

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Bibliographic Details
Main Authors: Junqing Sun, Shiyue Pan, Emma Karey, Yi-Je Chen, Kent E. Pinkerton, Christopher G. Wilson, Chao-Yin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
Subjects:
environmental tobacco smoke
autonomic function
nucleus ambiguus
SK channel
neuroplasticity
spiking activity
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.727000/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.727000/full

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