Diverse and Abundant Secondary Metabolism Biosynthetic Gene Clusters in the Genomes of Marine Sponge Derived Streptomyces spp. Isolates

The genus Streptomyces produces secondary metabolic compounds that are rich in biological activity. Many of these compounds are genetically encoded by large secondary metabolism biosynthetic gene clusters (smBGCs) such as polyketide synthases (PKS) and non-ribosomal peptide synthetases (NRPS) which...

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Bibliographic Details
Main Authors: Stephen A. Jackson, Lisa Crossman, Eduardo L. Almeida, Lekha Menon Margassery, Jonathan Kennedy, Alan D.W. Dobson
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/16/2/67