In-silico analysis of aging mechanisms of action potential remodeling in human atrial cardiomyocites

Electrophysiology of cardiomyocytes changes with aging. Agerelated ionic remodeling in cardiomyocytes may increase the incidence and prevalence of atrial fibrillation (AF) in the elderly and affect the efficiency of antiarrhythmic drugs. There is the deep lack of experimental data on an action poten...

Full description

Bibliographic Details
Main Authors: Nesterova Tatyana, Shmarko Dmitry, Ushenin Konstantin, Solovyova Olga
Format: Article
Language:English
Published: EDP Sciences 2020-01-01
Series:BIO Web of Conferences
Online Access:https://www.bio-conferences.org/articles/bioconf/full_html/2020/06/bioconf_icli2020_01025/bioconf_icli2020_01025.html