First Association of Interleukin 12 Receptor Beta 1 Deficiency with Sjögren’s Syndrome

First Association of Interleukin 12 Receptor Beta 1 Deficiency with Sjögren’s Syndrome

IntroductionInterleukin 12 receptor beta 1 (IL12Rβ1) deficiency is a primary immunodeficiency resulting mainly in susceptibility to opportunistic infection by non-tuberculous, environmental mycobacteria and severe infection caused by Salmonella spp. Till now, less than 300 patients with IL12Rβ1 defi...

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Bibliographic Details
Main Authors: Georgios Sogkas, Faranaz Atschekzei, Vivien Schacht, Christian von Falck, Alexandra Jablonka, Roland Jacobs, Matthias Stoll, Torsten Witte, Reinhold E. Schmidt
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
interleukin-12
interleukin-12 receptor beta 1 subunit
Sjögren’s syndrome
primary immunodeficiency
autoimmunity
Mendelian susceptibility to mycobacterial disease
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00885/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00885/full

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