CD40-mediated Activation of the NF-B2 Pathway

CD40 is a critical stimulatory receptor on antigen-presenting cells of the immune system. CD40-mediated activation of B cells is particularly important for normal humoral immune function. Engagement of CD40 by its ligand, CD154, on activated T cell membranes initiates a variety of signals in B cells...

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Bibliographic Details
Main Authors: Gail Abendroth Bishop, Bruce S Hostager
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00376/full