Gene expression profiling can predict the fate of HeLa cells exposed to X-ray irradiation with or without protoporphyrin accumulation

Protoporphyrin IX (PpIX) enhances the generation of reactive oxygen species in cells following physicochemical interactions with X-rays. To evaluate the use of porphyrins as radio-sensitizers in radiotherapy, the transcriptomic effects of PpIX and/or X-ray irradiation were investigated in HeLa cells...

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Bibliographic Details
Main Authors: Junko Takahashi, Masaki Misawa, Hitoshi Iwahashi
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Genomics Data
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596015001142