Transcriptional Factor Yin Yang 1 Promotes the Stemness of Breast Cancer Cells by Suppressing miR-873-5p Transcriptional Activity

Transcriptional Factor Yin Yang 1 Promotes the Stemness of Breast Cancer Cells by Suppressing miR-873-5p Transcriptional Activity

Transcription factor Yin Yang 1 (YY1) is upregulated in multiple tumors and plays essential roles in tumor proliferation and metastasis. However, the function of YY1 in breast cancer stemness remains unclear. Herein, we found that YY1 expression was negatively correlated with the overall survival an...

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Bibliographic Details
Main Authors: Qianqian Guo, Ting Wang, Yue Yang, Lanlan Gao, Qiong Zhao, Wenzhou Zhang, Tao Xi, Lufeng Zheng
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
YY1
miR-873-5p
HDAC
stemness
breast cancer
PI3K/AKT
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301797

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http://www.sciencedirect.com/science/article/pii/S2162253120301797

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