Ganglioside GD3 May Suppress the Functional Activities of Benign Skin T Cells in Cutaneous T-Cell Lymphoma

Ganglioside GD3 May Suppress the Functional Activities of Benign Skin T Cells in Cutaneous T-Cell Lymphoma

In cutaneous T-cell lymphoma (CTCL), which arises from skin-tropic memory T cells, malignant T cells and benign T cells are confined in the same skin lesions. It is thus difficult to evaluate the phenotypic characteristics and functional activities of benign T cells in CTCL. Disialoganglioside with...

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Bibliographic Details
Main Authors: Miki Kume, Eiji Kiyohara, Yutaka Matsumura, Hanako Koguchi-Yoshioka, Atsushi Tanemura, Yuma Hanaoka, Mifue Taminato, Hiroki Tashima, Koichi Tomita, Tateki Kubo, Rei Watanabe, Manabu Fujimoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
cutaneous T-cell lymphoma
ganglioside
GD3
resident memory T cells
antitumor immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.651048/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.651048/full

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