Lycopene antagonizes lead toxicity by reducing mitochondrial oxidative damage and mitochondria‐mediated apoptosis in cultured hippocampal neurons

Abstract Lead (Pb) exhibits serious adverse effects on the central nervous system, and the major pathogenic mechanism of Pb toxicity is oxidative stress. As one of the carotenoid family members with potent antioxidant properties, lycopene has shown its protections by inhibiting oxidative stress dama...

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Bibliographic Details
Main Authors: Mingyue Qu, Yanli Ni, Baoshi Guo, Xin Feng, Zheng Jiang
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:MedComm
Subjects:
Online Access:https://doi.org/10.1002/mco2.17