Loss of STAT3 in Lymphoma Relaxes NK Cell-Mediated Tumor Surveillance

Loss of STAT3 in Lymphoma Relaxes NK Cell-Mediated Tumor Surveillance

The transcription factors and proto-oncogenes STAT3 and STAT5 are highly activated in hematological malignancies and represent promising therapeutic targets. Whereas the importance of STAT5 as tumor promoter is beyond doubt, the role of STAT3 in hematological cancers is less well understood. Both, e...

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Bibliographic Details
Main Authors: Eva Maria Putz, Maria Agnes Hoelzl, Julia Baeck, Zsuzsanna Bago-Horvath, Christian Schuster, Brian Reichholf, Daniela Kern, Fritz Aberger, Veronika Sexl, Andrea Hoelbl-Kovacic
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Cancers
Subjects:
STAT3
lymphoma
BCR/ABL
NK cells
tumor immune surveillance
Online Access:http://www.mdpi.com/2072-6694/6/1/193

Internet

http://www.mdpi.com/2072-6694/6/1/193

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