Astrocytic GABA transporter activity modulates excitatory neurotransmission
Astrocytes monitor and regulate both excitatory and inhibitory synaptic activity. Here, the authors identify a novel form of neuronal-glia communication, by which astrocytes detect rises in GABA via the GABA transporter GAT-3; this results in adenosine release that acts presynaptically to inhibit ne...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms13572 |