A Functionally Different Immune Phenotype in Cattle Is Associated With Higher Mastitis Incidence

A Functionally Different Immune Phenotype in Cattle Is Associated With Higher Mastitis Incidence

A novel vaccine against bovine viral diarrhea (BVD) induced pathogenic antibody production in 5–10% of BVD-vaccinated cows. Transfer of these antibodies via colostrum caused Bovine neonatal pancytopenia (BNP) in calves, with a lethality rate of 90%. The exact immunological mechanisms behind the onse...

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Bibliographic Details
Main Authors: Karina Lutterberg, Kristina J. H. Kleinwort, Bernhard F. Hobmaier, Stefanie M. Hauck, Stefan Nüske, Armin M. Scholz, Cornelia A. Deeg
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
bovine neonatal pancytopenia
hyperproliferation
differential immune proteome
Concanavalin A
STAT
T helper pathways
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02884/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02884/full

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