Integrated pharmacokinetic–Pharmacodynamic (PK/PD) model to evaluate the in vivo antimicrobial activity of Marbofloxacin against Pasteurella multocida in piglets

Integrated pharmacokinetic–Pharmacodynamic (PK/PD) model to evaluate the in vivo antimicrobial activity of Marbofloxacin against Pasteurella multocida in piglets

Abstract Background Marbofloxacin is a veterinary fluoroquinolone with high activity against Pasteurella multocida. We evaluated it’s in vivo activity against P. multocida based on in vivo time-kill data in swine using a tissue-cage model. A series of dosages ranging from 0.15 to 2.5 mg/kg were admi...

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Bibliographic Details
Main Authors: Qing Lin Zeng, Xian Mei, Jia Su, Xiao Hong Li, Wen Guang Xiong, Yan Lu, Zhen Ling Zeng
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Veterinary Research
Subjects:
Marbofloxacin
PK/PD
P. Multocida
Tissue-cage model
Piglets
Online Access:http://link.springer.com/article/10.1186/s12917-017-1099-z

Internet

http://link.springer.com/article/10.1186/s12917-017-1099-z

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